Fragile X

What is Fragile ?
Fragile X is a genetic disorder that involves change in part of X chroosome inherited intellectual disability
(menatl retardation) in boys.
-Fragile X is also know as Autism
-More common in males than in females
-Martin Bell syndrome or Marker X syndrome

Quiz

1. What is Fragile X ?
2. What are 3 symptoms of Fragile X ?
3. Is Fragile X a disease or disorder?
4. How does this sydrome effect thet body ?
5. How do you get Fragile X ?

Work Cited

http://www.fragilex,org/html/history.htm
http://nicd.nih.ggov/publications/pubs/fragileX/sub6.cfm

History

-1910 Thomas Hunt Morgan demonstrates that when a gene is located on the X chromosome of the fruit fly, the characteristic appears more frequently in males than in females.
-1943 Martin Bell showed that a particular form of mental retardation is X-linked.
-1969 Herbert Lubs finals visual proof of the linkage if mental retardation and the X-chrormosome.

Causes

Causes of Fragile X is :

• Mutation to a certain gene named FMR1 that is responsible for making the protein that is imperative for brain development.
• FMR1 stands for "Fragile X Mental Retardation 1.
• This disorder is recessive
• The X chromrosome is involved in this syndrome. The female has two X chromosomes while the male only has one .
• Autosomal homozygous recessive

Treatment and Cure

There is no treatment or cure for Fragile X. There are medicenes that can be taken to reduce some sympoms, but nothing that can be done to fix it right now.

Diagnosis

Blood Test can be taken for diagnosis along with DNA test.